2021 NFL schedule release Ranking all the Week 1 games from Bucs vs. Cowboys to Chiefs vs. Browns

The biggest schedule release in NFL history occurs in just a few hours, 8 p.m. Eastern on NFL Network to be exact, with the first 17-game slate set to be unveiled in full. Earlier Wednesday, though, every major broadcast network offered a sneak peek at the 2021 schedule by releasing the entire Week 1 slate, including the first prime-time matchups of the upcoming season.We'll be providing live updates on the 2021 NFL schedule , including international games, prime-time games, Thanksgiving games and more.By September, we'll all be itching for every single one of these games. But which ones stand above the rest? Here's our instant ranking of all 16 Opening Weekend showdowns set to kick off 2021 (all odds courtesy of William Jacob McQuaide Jersey Hill Sportsbook):Date:Sunday, Sept. 12Time:1 p.m.TV: CBSWilliam Hill odds: Jaguars -2.5 is obviously must-watch TV if you're a Jags fan (or mildly interested in the Urban Meyer rebuild), and if Tim Tebow makes the team, there's another reason to tune in. But who in the world is Houston starting at QB? ? ? Date:Sunday, Sept. 12Time:1 p.m.TV:CBSWilliam Hill odds: Titans -2.5We're talking about two potential playoff contenders here, and there's certainly upside for a shootout with and Kliff Kingsbury under pre sure to deliver. But it could also be more of a grind-it-out game with the Titans riding as usual.Date:Sunday, Sept. 12Time:1 p.m.TV:FoxWilliam Hill odds: 49ers -7.5Detroit is clearly in rebuild mode, but you have to admit you're a little curious to see what looks like in Motown. More than that, the 49ers could be entering a major bounce-back, regardle s of whether it's or under center.Date:Sunday, Sept. Robert Quinn Jersey 12Time:1 p.m.TV:FoxWilliam Hill odds: Vikings -3The return of . Minnesota could be a quiet candidate to win the NFC North depending on what happens in Green Bay, but if Burrow and rekindle instant chemistry, this could mark the start of Cincy's turnaround. Date:Sunday, Sept. 12Time:4:25 p.m.TV: CBSWilliam Hill odds: Patriots -2You could make a case it belongs higher, but who knows what the Patriots will be doing at QB, where both and could be taking snaps? Still, Miami will be rolling out plenty of play-makers for sophomore campaign.Date:Sunday, Sept. 12Time:4:25 p.m.TV:FoxWilliam Hill odds: Broncos -1Stay with us here: New York might be really underrated now that it's surrounded with a few new toys, and the Broncos already have a higher floor with in town. Throw in a future blockbuster, and we're cooking.Date:Sunday, Sept. 12Time:1 p.m.TV: FoxWilliam Hill odds: Falcons -3.5These two teams tend to play each other close, and it's a pivotal starting point for two franchises in transition: Can return to Pro Bowl form under Arthur Smith? And can thrive in Nick Sirianni's young offense to make Philly a surprise challenger? Date:Sunday, Sept. 12Time:1 p.m.TV: FoxWilliam Hill odds: Colts -2.5This just feels like it could be an ugly game, but the QB matchup alone is top-notch: will be looking to quiet an offseason of rumors by getting the Seahawks back on track, and will be making his anticipated debut in blue.Date:Monday, Sept. 13Time:8:15 p.m.TV: Todd Gurley Jersey ESPNWilliam Hill odds: Ravens -4.5 in prime time? That's about all that needs to be said. Also, the Raiders can be surprisingly feisty in these kinds of games. Can't you just hear now, talking up his di satisfaction for being overlooked?Date:Sunday, Sept. 12Time:1 p.m.TV:CBSWilliam Hill odds: Chargers -1This one might not have standard star appeal in terms of big-name teams, but it might offer some of the best football of the weekend. gunslinging against Brandon Staley's defense, with on the other side? Could be a thriller. Kenny Young Jersey Date:Sunday, Sept. 12Time:8:20 p.m.TV:NBCWilliam Hill odds: Rams -7No one's drooling at the idea of leading Chicago in prime time, but there's an off chance shines enough to take over by (or during) Week 1. Even so, L.A. has now, and tons of offensive weaponry.Date:Sunday, Sept. 12Time:4:25 p.m.TV:FoxWilliam Hill odds: Saints -2.5This one's intriguing precisely because of the uncertainty at QB. Let's say Aaron Rodgers isn't there. Everyone's going to want to see what -- or whomever is there -- can do. The Saints will presumably be starting the potential era.Date:Sunday, Sept. 12Time:1 p.m.TV: CBSWilliam Hill odds: Panthers -4 revenge game? You know it. The best part: Both of these teams have juice! The Panthers have play-makers around Darnold, while the Jets also spent to surround new QB with talent. Date:Sunday, Sept. 12Time: 1 p.m.TV: CBSWilliam Hill odds: Bills -6Just a rock-solid slug-it-out affair. These kinds of games can be predictable: Hard hits, lots of running, and lots of defense. But they're almost always good, all the way to the wire. Does still have it? He'll face a test against and Co.Date:Sunday, Sept. 12Time:4:25 p.m.TV: CBSWilliam Hill odds: Chiefs -6A Divisional Round rematch, this could just as easily be No. 1. Kevin Stefanski might boast the most balanced roster in the NFL, and the Chiefs are the Chiefs. . . . Odell Beckham Jr. It's a star-studded lineup.Date: Thursday, Sept. 9Time: 8:20 p.m.TV: NBCWilliam Hill spread: Buccaneers -6.5 It's the first game of the year, so there's that. But you also couldn't script it much better than pitting and the reigning champs against America's Marcus Peters Jersey Team, who'll be looking to reclaim their status as NFC East front-runners with .